Use an Item Renderer to create a Component that will load up a given URL. The easiest way is to use the LinkButton Control

MainApplication.mxml

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4: 5: import mx.collections.ArrayCollection;
6: [Bindable]
7: public var myAC:ArrayCollection = new ArrayCollection([
8: {firstName:"Jon",lastName:"Hirschi",url:"http://www.workathomeseo.com"},
9: {firstName:"Tariq",lastName:"Ahmed",url:"http://www.mail4web.net"}
10: ]);
11:
12: ]]>
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urlRenderer.mxml

2: 3: label="Click On Me"
4: click="navigateToURL(new URLRequest(data.url))"/>
5: